Graphic representation of AEs

Produce a graphic representation of AE, counting AE as bars for each patient, colored by grade. Can be faceted by treatment arm.

ae_plot_grade_sum(
  df_ae,
  ...,
  df_enrol,
  low = "#ffc425",
  high = "#d11141",
  weights = NULL,
  arm = NULL,
  grade = "AEGR",
  subjid = "SUBJID"
)

Arguments

df_ae

adverse event dataset, one row per AE, containing subjid, soc, and grade.

...

unused

df_enrol

enrollment dataset, one row per patient, containing subjid (and arm if needed). All patients should be in this dataset.

low

the color of Grade 1 AE

high

the color of Grade 5 AE

weights

(optional) a length 5 numeric vector, giving the weights of each grade

arm

name of the treatment column in df_enrol. Case-insensitive. Can be set to NULL.

grade

name of the AE grade column in df_ae. Case-insensitive.

subjid

name of the patient ID in both df_ae and df_enrol. Case-insensitive.

Value

a ggplot

See also

ae_table_grade(), ae_table_soc(), ae_plot_grade(), ae_plot_grade_sum(), butterfly_plot()

Examples

tm = grstat_example()
attach(tm, warn.conflicts=FALSE)
ae_plot_grade_sum(df_ae=ae, df_enrol=enrolres)

ae_plot_grade_sum(df_ae=ae, df_enrol=enrolres, arm="ARM")

ae_plot_grade_sum(df_ae=ae, df_enrol=enrolres, arm="ARM", weights=c(1,1,3,6,10))